Development and critical period plasticity of the barrel cortex
نویسندگان
چکیده
منابع مشابه
Critical Period Plasticity Is Disrupted in the Barrel Cortex of Fmr1 Knockout Mice
Alterations in sensory processing constitute prominent symptoms of fragile X syndrome; however, little is known about how disrupted synaptic and circuit development in sensory cortex contributes to these deficits. To investigate how the loss of fragile X mental retardation protein (FMRP) impacts the development of cortical synapses, we examined excitatory thalamocortical synapses in somatosenso...
متن کاملBarrel Cortex Critical Period Plasticity Is Independent of Changes in NMDA Receptor Subunit Composition
The regulation of NMDA receptor (NMDAR) subunit composition and expression during development is thought to control the process of thalamocortical afferent innervation, segregation, and plasticity. Thalamocortical synaptic plasticity in the mouse is dependent on NMDARs containing the NR2B subunit, which are the dominant form during the "critical period" window for plasticity. Near the end of th...
متن کاملA critical period for experience-dependent synaptic plasticity in rat barrel cortex.
Recordings were made from neurons in layers II, III, and IV of rat barrel cortex. The animals were raised either from the day of birth (P0) or from P2, P4, or P7 with just the D1 vibrissa protruding on one side of the face and the contralateral side intact. Follicles were not ablated, but vibrissae were carefully removed by applying steady tension to the base of each vibrissa. Deprivation was c...
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Effect of Norepinephrine depletion on induction of experience dependent plasticity in male rat barrel cortex
Introduction: Barrel cortex of rats is a part of somatosensory cortex, which receives information from facial whiskers. Vibrisectomy by sensory deprivation leads to some changes in the barrel cortex, which have been known as experience dependent plasticity. On the other hand, Norepinephrine (NE) and locus coeruleus, which is the main source of NE, influenced response properties of cortical bar...
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ژورنال
عنوان ژورنال: European Journal of Neuroscience
سال: 2012
ISSN: 0953-816X
DOI: 10.1111/j.1460-9568.2012.08075.x